Overview

The Role of Synovitis in Osteoarthritis

Status:
Recruiting
Trial end date:
2020-03-01
Target enrollment:
0
Participant gender:
All
Summary
To determine whether platelet-rich-plasma (PRP) or HA (hyaluronic acid)injection into synovitis in osteoarthritis(OA) knee can achieve improvement in knee function and reduce synovitis.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Taipei Veterans General Hospital, Taiwan
Treatments:
Hyaluronic Acid
Criteria
Inclusion Criteria:

- diagnosed with OA knee according to ACR guideline

1. stiffness less than 30min

2. cracking sound during activity

3. more than 30min pain for last 2 months

4. non-bed ridden patients

5. no structure abnormality

6. synovitis was proved by US

Exclusion Criteria:

1. OA knee secondary to other disease 2 . more than 10 years after diagnosing OA 3. under
knee surgery within 3 months 4. autoimmune disease 5. refuses inform/consent process