The Role of Opioidergic Systems in Breathing Based Analgesia
Status:
Completed
Trial end date:
2017-06-27
Target enrollment:
Participant gender:
Summary
The purpose of this psychophysical and pharmacologic study is to determine if slow-breathing
induced pain relief is mediated by endogenous opioids in response to intravenous (IV)
administration of the opioid antagonist naloxone during noxious heat stimulation. We were
also interested in disentangling the endogenous analgesic mechanisms supporting
mindfulness-based analgesia.
Phase:
Early Phase 1
Details
Lead Sponsor:
University of California, San Diego Wake Forest University Health Sciences