The Role of Methylphenidate on Performance in the Cold

• Status: Active, not recruiting
• Trial end date: 2021-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose is to study the effects of dopamine activity, using methylphenidate ingestion, on exercise and cognitive function over the course of a progressive cooling protocol. The investigators hypothesize that methylphenidate will minimize the previously reported impairment in exercise performance and cognitive function with mild hypothermia and cold stress (air temperature: 0˚C) compared to placebo, suggesting that dopamine activity preserves exercise and cognitive capacity with mild hypothermia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Brock University
• Treatments: Methylphenidate

Criteria

Inclusion Criteria:

• Males and females

Exclusion Criteria:

• Diagnosed cardiovascular, respiratory, and/ or neuromuscular disease

• Prescription of MPH or any drugs for hyperactivity within the past 1 year

• Diagnosed mental health condition (e.g. depression, anxiety disorder)

• Raynaud's Disease or Cold Urticaria

• Current prescription medication (except for asthma or allergy medication)

• Pregnancy