The Role of Ketamine in Preventing Cognitive Dysfunctions in Postoperative Period of Cardiac Surgery

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to analyze the Ketamine with its anti-inflammatory profile would be able to prevent cognitive disorders in the postoperative period of cardiac surgery, since these disorders contribute to an impact on morbidity / mortality in this population.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Flavia orange
• Collaborator: Rebeca Gonelli Albanez da Cunha Andrade
• Treatments: Ketamine

Criteria

Inclusion Criteria:

• Patients aged over 50 years.

• Be submitted to cardiac surgery by sternotomy and with the use of cardiopulmonary bypass (CPB).

• American Society of Anesthesiologists classification 1, 2,3 and 4.

Exclusion Criteria:

• Patients undergoing reoperation.

• Patients undergoing heart transplantation.

• Patients using vasopressor agents and / or ionotropic continuous preoperatively.

• Patients with prior endotracheal intubation and consequently Ventilatory Assistance Mechanics.

• Patients with documented psychiatric disorders.

• Patients with previous cognitive disorders.

• Patients with a history of alcohol or drug abuse.

• Patients with a history of cerebrovascular accident (CVA) with less than 3 months.