The goal of this laboratory study is the examine the effect of mepolizumab drug on the health
and function of the cells lining the human nasal airways in vitro cell culture derived from
patients with chronic rhinosinusitis with nasal polyposis. The main questions the study aims
to study are:
1. To see what mepolizumab does to suppress inflammation of the human cells.
2. To see what mepolizumab does to maintain barrier integrity of epithelial cells