The Role of Estrogen in Luteinizing Hormone Surge and Ovulation
Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to establish that sustained estrogen levels are the driving force
for the LH surge, and are thereby necessary for ovulation to occur. We predict that by
reducing levels of circulating estrogen, letrozole, an aromatase inhibitor, will inhibit
ovulation from occurring.