The Role of Contrast Enhanced Ultrasound in Appendicitis

• Status: Active, not recruiting
• Trial end date: 2022-03-18
• Target enrollment: 0
• Participant gender: All

Summary

This study seeks to determine the efficacy of Contrast Enhanced Ultrasound (CEUS) in improving the diagnosis of acute appendicitis in children, when compared to the standard grey-scale ultrasound.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Mercy Hospital Kansas City

Criteria

Inclusion Criteria:

• Present to Children's Mercy Adele Hall campus with a clinical concern for acute appendicitis

• Age 8 through 17 years

• seen between Institutional Review Board (IRB) approval date and 12/31/2019

• Seen Monday- Friday between the hours of 9:00 a.m. and 4:00 pm

• Has had an IV catheter placed as part of their standard of care

Exclusion Criteria:

• Known cardiac abnormality

• Pulmonary hypertension

• Known sensitivity to sulfur hexafluoride, polyethylene glycol 4000, distearoylphosphatidylcholine (DSPC), dipalmitoylphosphatidylglycerol sodium (DPPG-Na), or palmitic acid

• Does not had an IV catheter placed

• Unable to roll over

• Unable to assent

• Pregnant

• Lactating

• Received an ultrasound image from a referring facility