Overview

The Role of COX-2 Inhibition in Salt Sensitivity of Blood Pressure

Status:
Completed
Trial end date:
2009-01-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to determine if the drug Celebrex changes the way the kidney gets rid of salt and maintains blood pressure.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Delaware
Collaborator:
Christiana Care Health Services
Treatments:
Celecoxib
Criteria
Inclusion Criteria:

- healthy men and women

Exclusion Criteria:

- history of heart disease

- have had heart surgery

- high blood pressure

- diabetes

- cancer

- any other disease such as kidney or neurological diseases

- taking medications such as aspirin or medicines for your heart or blood pressure

- have asthma or are allergic to sulfa drugs

- body mass index greater than 30

- use tobacco

- pregnant

- women using oral contraceptives or hormone replacement therapy