The Role of Antibiotics in Full Thickness Skin Graft Survival for Facial Reconstructive Surgery
Status:
Recruiting
Trial end date:
2024-09-01
Target enrollment:
Participant gender:
Summary
Antibiotics are sometimes prescribed to patients who have had reconstructive surgery of
wounds on their face using skin grafts. But, it is not yet known whether antibiotics improve
the healing of skin grafts and reduce the risk of infections after surgery in these patients.
It is known that antibiotics, like all medications, have side-effects although these are
rare. This research study is designed to show us whether antibiotics improve wound healing or
not, so that we may determine if we should continue using antibiotics even if they have
side-effects in some patients.
Our hypothesis is that patients treated with post-operative, systemic antibiotics will
demonstrate a statistically significant improvement in the survival of their facial full
thickness skin grafts compared to patients who are not treated with systemic antibiotics.