The Role of Antibiotic Prophylaxis in Cleft Palate and Velopharyngeal Insufficiency Repair
Status:
Withdrawn
Trial end date:
2018-03-01
Target enrollment:
Participant gender:
Summary
Cleft Lip and Palate surgical repair is one of the most common procedures performed by
Plastic and Reconstructive Surgeons in the World. With this in mind, it is curious that no
consensus exists regarding the usage of postoperative antibiotics or the effects this might
have on wound complications such as cellulitis, dehiscence, or fistula formation. The
surgical bed in cleft lip/palate repair is known to harbor a myriad of pathological
organisms, indeed the human bite is one of the more clinically and microbiologically
significant injuries to treat. This research study is to elucidate the role, if any, that
prophylactic antibiotics have in the prevention of complications post cleft palate (CP) and
VPI repair and potentially establish a new paradigm of care.