The Role of 5-Fluorouracil in Post-Operative Scar Formation Following Direct Brow Ptosis Repair
Status:
Unknown status
Trial end date:
2020-08-01
Target enrollment:
Participant gender:
Summary
This is a double (physician and patient) blinded randomized controlled clinical trial in
which patients who have undergone bilateral direct brow ptosis repair undergo a trial in
which one of brow is injected with placebo 0.9% Normal Saline and the contra-lateral brow is
injected with 0.3-0.6 mL over the entire brow of 50mg/mL 5-Fluorouracil sub-dermal
injections. The researchers aim to investigate whether injecting 5-Fluorouracil preemptively
will not only accelerate wound healing and decrease hypertrophic scar formation compared to
placebo, but also improve overall scar appearance in a safe manner.