The Risk of Bleeding After Removal of Large Colorectal Polyps in Patients Taking Aspirin
Status:
Unknown status
Trial end date:
2015-09-01
Target enrollment:
Participant gender:
Summary
The risk of bleeding after polypectomy of large colorectal polyps in patients taking aspirin
is uncertain. This is a randomized, multi-center, placebo-controlled, double-blind study to
compare the risk of significant bleeding after endoscopic polypectomy of large (>=10mm)
colorectal polyps in patients continuing or discontinuing on daily acetylsalicylic acid (ASA)
use. Eligible patients will be randomly assigned in a 1:1 ratio to a group taking 75mg daily
ASA or placebo 7 days before and 14 days following polypectomy. The primary endpoint of the
study is bleeding within 30 days from colorectal polypectomy. The secondary endpoints are
composite cardiovascular events occurring between the date of randomization and 30 days after
polypectomy.
Phase:
Phase 4
Details
Lead Sponsor:
Maria Sklodowska-Curie Institute - Oncology Center Maria Sklodowska-Curie Memorial Cancer Center, Institute of Oncology