Overview
The Proton Pump Inhibitor (PPI) Test for the Extraesophageal Manifestation of GERD
Status:
Unknown status
Unknown status
Trial end date:
1969-12-31
1969-12-31
Target enrollment:
0
0
Participant gender:
All
All
Summary
PPI test;empirical trial with high-dose proton-pump inhibitors (PPIs) has been shown to be a sensitive tool for diagnosing patients with GERD. However, this diagnostic strategy has not been well established in patients with extraesophageal manifestation of GERD. In this study, we aim to see the relevance of PPI test in diagnosing GERD in patients with extraesophageal symptoms.Phase:
N/AAccepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Samsung Medical CenterTreatments:
Proton Pump Inhibitors
Rabeprazole
Criteria
Inclusion Criteria:- Patients with extraesophageal manifestation symptoms of GERD
Exclusion Criteria:
- laryngeal, pharyngeal, liver, lung, renal, or hematological disorders
- a history of gastrointestinal surgery, and a history of connective tissue disorders.
- patients with duodenal or gastric ulcers as well as other significant lesions, such as
gastric cancer, esophageal cancer, or subepithelial tumors more than 1 cm observed on
the upper endoscopy