The Protective Effects of Sevoflurane in Pediatric Cardiac Surgery
Status:
Unknown status
Trial end date:
2012-01-01
Target enrollment:
Participant gender:
Summary
During repair of a congenital heart defect the child is exposed to myocardial hypoxia. Recent
studies have suggested that the paediatric myocardium is more sensitive to hypoxia and
cardioplegic arrest than the adult. The protective effect of halogenated agents on ischaemia
and reperfusion injury has been investigated widely in adults. The investigators hypothesis
that sevoflurane applied during cardiopulmonary bypass might afford better myocardial
protection during paediatric cardiac surgery.