Overview

The Protective Effect of Ginkgo Biloba Extract on Cisplatin-induced Ototoxicity in Humans

Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
0
Participant gender:
All
Summary
The proposal of this study was to evaluate in human beings, using distortion product otoacoustic emission (DPOAE) test, the action of ginkgo biloba extract (GBE761)as a possible ear protective against cisplatin (CDDP) induced hearing loss.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of Brasilia
Treatments:
Cisplatin
Criteria
Inclusion Criteria:

- Over the age of eighteen

- Patients that will begin treatment with cisplatin

- No prior treatment with cisplatin

Exclusion Criteria:

- Individuals with middle ear, cochlear or retrocochlear disease

- Presence of changes in pure tone audiometry and/or distortion-product otoacoustic
emissions