The Prophylactic Role of Tranexamic Acid in High Risk Pregnant Women Undergoing Elective Cesarean Section in Prevention of Postpartum Hemorrhage

• Status: Not yet recruiting
• Trial end date: 2023-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of the study is to assess the prophylactic role of tranexamic acid in reducing blood loss during and after elective cesarean section delivery in high risk patients.

Comparing effect of administration of 1gm of TXA half an hour before elective C-section , effect of administration of 1gm of TXA on the start of uterine incision and placebo effect, Where in all an addition of prophylactic uterotonics is given, in a randomized control, double blind trial of 3 groups.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• High risk women undergoing elective C-section

• Hypertensive patients.

• Obese patients.

• Patients on LMWH.

• Transverse lie

• DM ( Type 1 & Gestational )

• Cardiac ( Not on Anticoagulants )

• Placenta Previa ( Not in PAS )

• Previous uterine scar ( > previous 2 C- section )

Exclusion Criteria:

• Patients with bleeding tendency.

• HELLP Syndrome.

• Emergency C- section.

• Mechanical prosthetic valve

• Atrial Fibrillation.

• Allery to tranexamic acid

• Placenta Accreta , Increta , percreata.