The Progression From Dysmenorrhoea to Chronic Pelvic Pain

• Status: Unknown status
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

This is a cross-sectional observational study.

For participants resident in Adelaide, South Australia.

The study consists of 3 visits to the Pain and Anaesthesia Research Clinic (PARC), within the Royal Adelaide Hospital (RAH).

A total of 56 participants will be recruited for this study.

• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Adelaide
• Treatments: Contraceptive Agents

Criteria

Inclusion Criteria:

• Age between 16 to 35 years old

Exclusion Criteria:

• Irregular menstrual cycles

• Use of any reproductive hormonal preparations (other than the combined oral contraceptive pill), thyroxine, insulin or corticosteroids

• Presence of an inflammatory process, or clinically significant infection in the 4 weeks

• Clinically significant renal, hepatic, cardiac, auto-immune disease

• Current use of immunosuppressant medication such as hydroxychloroquine, methotrexate or azathioprine

• Inability to read or comprehend the written information provided

• Current use of medications known to affect TLR responsiveness including amitriptyline or minocycline

• Current use of any analgesics, including non-steroidal anti-inflammatory medications and opioids for 5 drug half-lives prior to the day of testing

• Current or previous pregnancy

• Body Mass index less than 18 or more than 30