The Preventive Effect of Shenfu Injection on Myocardial Dysfunction in Sepsis
Status:
RECRUITING
Trial end date:
2026-09-30
Target enrollment:
Participant gender:
Summary
This study focuses on improving heart function in patients with life-threatening blood infections (septic shock). When the body fights severe infections, the heart sometimes struggles to pump blood effectively, which can lead to dangerous complications. Current treatments like intravenous fluids and blood pressure medications have limitations in protecting heart function.
This multicenter clinical trial aims to evaluate whether adding Shenfu Injection - a traditional Chinese medicine preparation widely used to enhance cardiac function in cardiovascular diseases - to standard therapies can:
1. Prevent myocardial dysfunction during septic shock
2. Accelerate cardiac recovery if complications occur
3. Improve overall survival and clinical outcomes The randomized controlled design will compare therapeutic effects between two groups: one receiving standard septic shock treatment alone, and the other receiving standard treatment combined with Shenfu Injection.
Phase:
PHASE4
Details
Lead Sponsor:
First Affiliated Hospital of Wannan Medical College
Collaborators:
Chaohu Hospital of Anhui Medical University Fuyang people's hospital Fuyang Traditional Chinese Medicine Hospital Guangde people's hospital Suzhou Municipal Hospital of Anhui Province Taihe County Traditional Chinese Medicine Hospital The First Affiliated Hospital of Anhui Medical University The First People's Hospital of Bengb The Fourth Affiliated Hospital of Anhui Medical University The Second Hospital of Anhui Medical University the Second of Affiliated Hospital of Wannan Medical College, Wuhu, China The Third People's Hospital of Bengbu Tongling People's Hospital Wuhu City Second People's Hospital Wuhu County Traditional Chinese Medicine Hospital Wuhu first people's hospital Xuancheng people's hospital