The Prevention of Systemic Ectopic Mineralization in Pseudoxanthoma Elasticum
Status:
Recruiting
Trial end date:
2027-04-29
Target enrollment:
Participant gender:
Summary
The goal of this randomized clinical trial is to assess the effect of etidronate on ectopic
calcification in relatively young patients with Pseudoxanthoma elasticum. The main question
it aims to answer are:
What is the difference in the arterial calcification scores in the legs and the carotid
syphon measured on low-dose CT scan after 24 months of treatment compared to baseline between
etidronate and placebo.
Participants will be asked to do take etidronate or placebo for 24 months.