The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial
Status:
Completed
Trial end date:
2017-07-01
Target enrollment:
Participant gender:
Summary
Delirium is a medical term or condition that includes a temporary inability to focus
attention and to think clearly. Delirium occurs commonly (10% to 70%) in patients older than
60 undergoing large surgeries. The purpose of this study is to test rigorously whether a drug
called ketamine can decrease the chance that patients will experience delirium after their
surgery. The investigators are also testing whether ketamine decreases postoperative pain,
postoperative opioid consumption, postoperative nausea and vomiting, ICU and hospital length
of stay, and adverse outcomes (e.g. hallucinations and nightmares).
Phase:
Phase 3
Details
Lead Sponsor:
Washington University School of Medicine
Collaborators:
Asan Medical Center Harvard Medical School Harvard Medical School (HMS and HSDM) Medical College of Wisconsin Memorial Sloan Kettering Cancer Center Postgraduate Institute of Medical Education and Research University Health Network, Toronto University of Bern University of Manitoba University of Michigan Virginia Mason Hospital/Medical Center Weill Medical College of Cornell University
Treatments:
Anesthetics Hypnotics and Sedatives Ketamine Polystyrene sulfonic acid