The Pharmacokinetics of Fentanyl in Intensive Care Patients
Status:
Unknown status
Trial end date:
2017-11-01
Target enrollment:
Participant gender:
Summary
This study is part of a project intended to develop guidelines to optimise the dosing of
fentanyl in intensive care patients.
This study will focus on determining:
- Whether the pharmacokinetics of fentanyl change during the ICU stay.
- To what extent / the degree of change in fentanyl pharmacokinetics in ICU patients.
- Which factors (e.g. physiological variables) that cause such a change.
- Based on simulations, determine context-sensitive half-times of fentanyl in ICU
patients.