The PROMPT Pilot Study is a feasibility mixed methods prospective cohort study following
principles of community-based participatory action research. The study recruited 80 people
who use drugs and followed them for 6 months while providing access to counselling, nicotine
replacement therapy and peer-support in a community setting. A notable reduction in average
cigarette use per day (20.5 to 9.3) and illicit substance use (18.8%) was observed at
study-end. PROMPT's patient engagement model is an effective harm-reduction strategy for the
growing opioid use crisis and can improve the health outcomes of marginalised at-risk
populations worldwide.