The Oxygenation of the Brain During Caesarean Section

• Status: Completed
• Trial end date: 2012-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine the impact of phenylephrine versus ephedrine on organ perfusion, in women undergoing caesarean section receiving spinal anaesthesia. The organ perfusion is estimated by measuring the maternal cerebral oxygenation by NIRS(Near-infrared spectroscopy)and the foetal heartrate.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Naestved Hospital
• Collaborator: Rigshospitalet, Denmark
• Treatments: Ephedrine; Oxymetazoline; Phenylephrine; Pseudoephedrine

Criteria

Inclusion Criteria:

• Healthy pregnant women

• Over 18 years old

• ASA 1-2

• Undergoing elective caesarean section

• Height over 160 cm or under 180 cm

Exclusion Criteria:

• Allergic reactions to ephedrine or phenylephrine

• High blood levels of bilirubin

• HELPP syndrome

• Preeclampsia (pregnancy-induced hypertension)

• Non singleton pregnancies