The Optimal Time for Intravenous Antibiotic Prophylaxis in Elective Cesarean Section
Status:
Unknown status
Trial end date:
2016-09-01
Target enrollment:
Participant gender:
Summary
Objective: To determine the optimal time for intravenous antibiotic prophylaxis
administration in pregnant women undergoing elective cesarean section to minimize postpartum
infectious complication for both the mother & neonate.
Study Design: A randomized comparative study. Setting: The Obstetrics and Gynecology
department of Kasr El Aini hospital (Cairo University - Egypt) in the period from April 2016
to September 2016.
Methodology: Six hundred pregnant women aged from 20 to 40 years old with singleton living
healthy fetuses undergoing elective lower segment caesarean section (LSCS).They will be
randomized into three groups: group A in which 200 women will receive IV ceftriaxone (2g) 60
minutes before skin incision, group B in which 200 women will receive IV ceftriaxone (2g)
immediately with skin incision & group C in which 200 women will receive IV ceftriaxone (2g)
immediately after umbilical cord clamping. Outcomes include postoperative maternal & fetal
infectious morbidity.