Overview The Optimal Long Term Treatment Strategy of Anti-resorptive Medications---The Extension of Denosumab Sequential Therapy Status: Recruiting Trial end date: 2030-12-31 Target enrollment: Participant gender: Summary This study is to investigate whether the alternating use of Prolia (Denosumab) and Aclasta (Zoledronic acid) can continue to increase bone density. Phase: Phase 4 Details Lead Sponsor: National Taiwan University HospitalTreatments: DenosumabZoledronic Acid