The OMEGA Study: Use of Eye Drops to Treat Geographic Atrophy Associated With Age-Related Macular Degeneration (Dry AMD)

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this trial is to compare the ability of two doses of OT-551 ophthalmic solution and drug-free solution to safely and effectively treat geographic atrophy associated with age-related macular degeneration.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Othera Pharmaceuticals
• Treatments: Ophthalmic Solutions; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• have a clinical diagnosis of GA in one or both eyes;

• be of non-childbearing potential

Exclusion Criteria:

• have GA secondary to any condition other than AMD in the study eye;

• have a BCVA of 20/200 or worse in the non-study eye;

• have a history of or current choroidal neovascularization in either eye, or the need for any study eye anti-angiogenic therapy;

• have any ocular condition in the study eye that would progress during the course of the study and could affect central vision or other ocular conditions that may be a confounding factor in this study;

• need to wear contact lenses in the study eye during the study;

• had confounding ocular surgery in the study eye;

• have concomitant treatment with any systemic or ocular medication that is known to be toxic to the lens, retina, or optic nerve;