The Neuroprotective Effects of Methylphenidate and Atomoxetine in Children With ADHD: A Lipidomic Study
Status:
Not yet recruiting
Trial end date:
2022-07-31
Target enrollment:
Participant gender:
Summary
1. To identify the difference in the lipidomic profiles between ADHD and controls;
2. To examine the effects of methylphenidate and atomoxetine on the lipidomic profiles in
ADHD, and the relationship between medication-related changes in the lipidomic profiles
and medication-related improvements in the behavioral symptoms and neuropsychological
functions;
3. To map medication-related lipidomic biomolecules to their respective metabolic pathways
to identify the underlying mechanisms of neuroprotective effects of methylphenidate and
atomoxetine.