The Mechanism of Dexmedetomidine in Improving Delirium After Cardiac Surgery

• Status: Unknown status
• Trial end date: 2020-08-31
• Target enrollment: 0
• Participant gender: All

Summary

The investigators aim to evaluate the roles of α7nAchR in the mechanisms of dexmedetomidine in improving delirium after cardiac surgery. The results of this study would lay the foundation for revealing the mechanisms of dexmedetomidine improving delirium after cardiac surgery and provide a new idea to the early treatment of delirium.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nanjing First Hospital, Nanjing Medical University
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• ICU patients underwent cardiac surgery

• age ≥ 60 years

Exclusion Criteria:

• Preoperative cognitive decline, mental illness,

• preoperative long-term use of hormone patients,

• preoperative alcohol dependence,

• patients with alcohol withdrawal symptoms