The Interest of the Xylocaine® and Ketamine on the Management of Acute and Chronic Ain After Colectomy by Laparoscopy
Status:
Completed
Trial end date:
2017-09-01
Target enrollment:
Participant gender:
Summary
Recent clinical studies in abdominal surgery have shown that the use of Xylocaine®
parenterally intraoperative at plasma concentrations below the toxic threshold of 5 .mu.g /
ml, had an analgesic effect and decreased postoperative morphine consumption.
This study aims to evaluate the activity of Xylocaine® and ketamine separately administered
parenterally, in terms of postoperative morphine consumption and decrease incidences of
postoperative chronic pain at 3 and 6 months after laparoscopic colectomy compared the
placebo group.
The evaluation of the intensity of postoperative pain, hyperalgesia perished skin surface
scarring) and pain perception threshold by Pain Matcher® confirm or not the predictive nature
of these criteria in the occurrence of chronic pain.