The Interaction Between Oxytocin and Serotonin

• Status: Unknown status
• Trial end date: 2019-07-15
• Target enrollment: 0
• Participant gender: Male

Summary

the study aims to explore whether there is an interaction between oxytocin and serotonin in the regulation of emotion-based behavior by using a between-subject randomized double blind pharmacological fMRI design during which 4 groups of healthy male subjects will receive combinations of oxytocin nasal-spray (versus placebo) and acute tryptophan depletion (ATD, versus placebo)

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Electronic Science and Technology of China
• Treatments: Oxytocin; Serotonin; Tryptophan

Criteria

Inclusion Criteria:

• health subjects without past or current psychiatric or neurological disorders

• Right-handedness

Exclusion Criteria:

• History of head injury;

• Medical or psychiatric illness.

• High blood pressure, general cardio-vascular alterations

• History of drug or alcohol abuse or addiction.

• Allergy against medications or general strong allergies

• Sleep disorders.

• Visual or motor impairments