Overview

The Interaction Between Diabetes and Estradiol on Human Brain Metabolism in Postmenopausal Women

Status:
Completed
Trial end date:
2021-07-19
Target enrollment:
Participant gender:
Summary
The primary aim of this study is to test whether type 2 diabetes interacts with estradiol on brain metabolism in vivo in humans. This will be accomplished by imaging brain metabolism using positron emission tomography before and after short-term administration of transdermal 17β-estradiol in 10 postmenopausal women with diabetes and 10 non-diabetic postmenopausal women.
Phase:
Phase 1
Details
Lead Sponsor:
Wake Forest University Health Sciences
Collaborator:
National Institute on Aging (NIA)
Treatments:
Estradiol
Estradiol 17 beta-cypionate
Estradiol 3-benzoate
Estradiol valerate
Polyestradiol phosphate