The Influence of Helicobacter Pylori Eradication on Gastric Pathology: a Long-term, Prospective Cohort Study

• Status: Not yet recruiting
• Trial end date: 2031-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Helicobacter pylori (H. pylori) infection, affecting an estimated 50% of the global population, is a main cause of chronic gastritis, peptic ulcers and gastric cancer. By causing progressive damage to the stomach and may eventually result in gastric atrophy, H. pylori infection has been demonstrated to be responsible for more than 95% of gastric malignancies

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shandong University

Criteria

Inclusion Criteria:

• Patients with H. pylori infection;

• Aged 18-65 years.

Exclusion Criteria:

• Patients with gastrectomy, acute GI bleeding and advanced gastric cancer;

• Conditions unsuitable for performance of gastroscopy, such as coagulopathy, impaired renal function;

• Pregnancy or breastfeeding;

• Inability to provide informed consent and other situations that could interfere with the examination or therapeutic protocol.