The Influence of Ezetimibe on Gallbladder Function

• Status: Withdrawn
• Trial end date: 2009-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Ezetimibe is a drug which inhibits the absorption of both dietary and biliary cholesterol in the small intestine. Ezetimibe has been approved for use in humans to lower serum cholesterol.

The primary aim of this study is to determine if ezetimibe normalizes resting and residual volume in patients with chronic acalculous cholecystitis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Indiana University
• Treatments: Ezetimibe

Criteria

Inclusion Criteria:

• Subjects with typical biliary pain and ejection fraction <30% on a HIDA scan.

• Must be > 18 years of age.

Exclusion Criteria:

• Subjects with gallstones seen on HIDA.

• Subjects on statin medication

• Subjects with known allergies to ezetimibe.

• Subjects who are pregnant or breast-feeding.