The Influence of Energy Drinks on the Blood Oxygenation Concentration of the Optic Nerve

• Status: Unknown status
• Trial end date: 2014-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The present proposal investigates the influence of energy drinks on the blood oxygenation concentration of the optic nerve on healthy subjects. On a voluntary basis, 15 subjects, man or woman, will be selected to undergo this experiment. Many factors can influence the blood oxygenation concentration of the optic nerve, which will be measured also during this experiment, namely: Intra ocular pressure (IOP), blood pressure, heart rate and systemic hemoglobin saturation.

The subjects will have to be tested twice to test the two conditions of this experiment:

1. The effect after the intake of a can of Redbull (250 ml)

2. The difference with the intake of 250 ml of water

The purpose of this study is to determine if the blood oxygenation concentration of the optic nerve varies after having ingested 250 ml of Redbull.

Our hypothesis are:

1. The blood oxygenation concentration of the optic nerve measured with OSOME (see detailed description below), decreases due to the consumption of the energy drink Redbull compared to an equal volume of water.

2. The IOP measured with iCare tonometer decreases after the consumption of the energy drink Redbull compared to an equal volume of water.

3. The systemic blood pressure, measured with an automatic sphygmomanometer remains constant after ingestion of Redbull energy drink or an equal volume of water.

4. Heart rate, measured with a sphygmomanometer automatic increases after taking a Redbull energy drink compared to an equal volume of water.

5. The rate of systemic hemoglobin saturation measured with a pulse oximeter remains constant after the ingestion of a Redbull energy drink or an equal volume of water.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Université de Montréal

Criteria

Inclusion Criteria:

• Be a man or a woman in good general health

• Be a non-smoker

• Weigh between 45 kg and 80 kg

• Have an intra ocular pressure inferior to 22 mm Hg

• Have a blood pressure inferior to 120/80 mm Hg

• Absence of systemic diseases (including hypertension, diabetes, or vascular disease),

• Absence of any ocular disease

• Evidence of abstinence from caffeine or caffeine beverages 48 hours prior to the experiment

• Abstinence from use of any systemic drugs and/or alcohol

Exclusion Criteria:

• Any subject who has family or personal history of glaucoma will be excluded

• All the subjects who didn't respect the inclusion criteria

There is no monetary compensation for participating in this study.