Overview

The Influence of AMH on Ovarian Responsiveness to Ovulation Induction With GnRH in Women With PCOS

Status:
Unknown status
Trial end date:
2016-08-01
Target enrollment:
0
Participant gender:
Female
Summary
The investigator suggests that PCOS women with high AMH levels are resistant to ovarian stimulation and may need adjustment of the dose of gonadotrophin.
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Ain Shams Maternity Hospital
Treatments:
Triptorelin Pamoate
Criteria
Inclusion Criteria:

- Women of age 18 - 35 years

- BMI 20 - 30 kg/m2

- Anovulatory infertility

- Diagnosis of PCOS based on Rotterdam consensus criteria (two of three criteria:
Oligo/anovulation, hyperandrogenaemia and sonographic appearance of polycystic
ovaries)

Exclusion Criteria:

- Women Above 35 years or under 18 years

- Women with BMI above 30 kg/m2 or under 20 kg/m2

- Normally ovulating women

- Patients with marked hyperandrogenaemia were screened for congenital adrenal
hyperplasia (by measuring serum concentration of 17alpha hydroxyl-progesterone) or
Patients with Cushing syndrome (by measuring urinary free cortisol)