The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID)
Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
This study is a randomized placebo-controlled trial comparing two antibiotic treatment
regimens for acute PID. Women with acute PID will be randomized to one of two treatment
regimens: 1) a single intramuscular dose of ceftriaxone 250 mg, doxycycline 100 mg orally
twice a day for 14 days, along with placebo tablets orally twice a day for 14 days or 2) same
doses of ceftriaxone and doxycycline, and metronidazole 500 mg orally twice a day for 14
days. The primary objective is to compare the eradication of anaerobic organisms from the
upper genital tract between women who receive standard outpatient antibiotic treatment to
those who receive standard outpatient treatment along with a two-week course of
metronidazole.
Phase:
Phase 2
Details
Lead Sponsor:
Harold Wiesenfeld
Collaborator:
National Institute of Allergy and Infectious Diseases (NIAID)