The Impact of Vitamin D Supplementation on Glucose Metabolism in Chinese Women With Former Gestational Diabetes Mellitus

• Status: Unknown status
• Trial end date: 2019-01-31
• Target enrollment: 0
• Participant gender: Female

Summary

Vitamin D deficiency are related to insulin resistance and impaired beta-cell function.It is reported that the level of vitamin D is lower during pregnancy and postpartum in the women with Gestational Diabetes Mellitus. The investigators hypothesize that vitamin D supplementation to women after birth with previous gestational diabetes may improve glucose metabolism.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
• Treatments: Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

1. with previous GDM,40-50 days after birth -

2. with deficiency of vitamin D(25-(OH)D3<50nmol/L)

Exclusion Criteria:

1. type 1 diabetes，type 2 diabetes and other type of diabetes

2. server disfunction of liver and kidney（ALT >100U/L，Cr>132ummol/L）

3. with mental disease,sever anemia,sever infection,sever heart disease,now is taking asprin, immunosuppressive agent,Antiepileptic drugs

4. pregnancy or plan to pregnant in one year

5. can't understand the requirement of this study

6. disfunction of thyroid