The Impact of Topical Prostaglandins on the Biomechanical Properties of the Cornea in Patients With Open Angle Glaucoma

• Status: Completed
• Trial end date: 2016-11-16
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the influence of topical prostaglandin analog (PGA) medication on corneal biomechanical properties in patients undergoing PGA treatment for open-angle glaucoma.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Maisonneuve-Rosemont Hospital

Criteria

Inclusion Criteria:

• patients with bilateral open angle glaucoma on monotherapy with topical PGA medication in both eyes

Exclusion Criteria:

• corneal disease (such as Fuchs' endothelial dystrophy or keratoconus)

• past history of corneal trauma or surgery (including refractive surgery) that may affect hysteresis measurements

• contact lens wearers

• uncontrolled glaucoma or advanced visual field (VF) damage (mean defect < -12.0 db)

• patients taking systemic prostaglandin medication, non-steroidal anti-inflammatory drugs, or undergoing hormone replacement therapy