The Impact of Subcutaneous Glucagon Before, During and After Exercise a Study in Patients With Type 1 Diabetes Mellitus
Status:
Completed
Trial end date:
2017-07-11
Target enrollment:
Participant gender:
Summary
This project is part of several studies exploring situations, where glucagon potential has
lesser glucose elevating effect. Exercise can be one of these situations as exercise may
reduce liver glycogen depots.
The investigators aims are:
1. To compare the increase in plasma glucose after 200µg glucagon given either after
exercise or after resting for 45 minutes.
2. To determine whether a subcutaneous glucagon injection just before exercise has a
greater impact on hepatic glucose production and thereby is superior to an injection
after exercise in preventing hypoglycemia during and two hours after exercise.
3. To compare the accuracy of two Dexcom G4 continuous glucose monitors, (CGM) placed at
either the abdominal wall or on the upper arm.