The Impact of Preoperative Olanzapine on Quality of Recovery After Discharge From Ambulatory Surgery
Status:
Not yet recruiting
Trial end date:
2026-01-01
Target enrollment:
Participant gender:
Summary
The primary objective of this phase 2 randomized controlled trial is to determine whether the
pre-operative administration of olanzapine (5 mg PO) improves quality of recovery (assessed
by the Quality of Recovery-40 (QoR-40) survey) on postoperative day 1 in patients having
ambulatory surgery with general anesthesia.
The secondary objectives of this study are to determine whether there are differences in
quality of recovery on postoperative day 2, presence of post-discharge nausea, presence of
severe post-discharge nausea, recovery room length of stay and opioid consumption in patients
who receive the study drug versus placebo.