The Impact of Fitness on Vascular Dysfunction in Adolescents With Type 1 Diabetes
Status:
Completed
Trial end date:
2013-11-01
Target enrollment:
Participant gender:
Summary
The principal hypothesis of this study is that the micro and macro vasculature of young
diabetes mellitus type 1 (DM1) patients is particularly susceptible to atherogenic factors
which cause vascular dysfunction at multiple levels of the arterial vasculature and that this
dysfunction is demonstrable using state-of-the-art ultrasound methods. The investigators
further hypothesize that interventions, such as exercise, that are readily integrated into
the daily life of individuals with DM1 can mitigate or reverse these early vascular changes
and thereby diminish the otherwise predictable longer-term development of cardiovascular
disease (CVD) in type 1 DM