The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
Status:
Not yet recruiting
Trial end date:
2033-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the hypothesis that the anti-depressant and
anti-suicidal effects of the N-methyl-D-aspartate receptor (NMDAR) antagonist Ketamine is
critically dependent on stimulation of Alpha-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic
Acid receptors (AMPAR).
Phase:
Phase 2
Details
Lead Sponsor:
Yale University
Collaborators:
American Foundation for Suicide Prevention National Center for PTSD VA Connecticut Healthcare System