Overview

The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain

Status:
Unknown status
Trial end date:
2012-12-01
Target enrollment:
0
Participant gender:
All
Summary
Vitamin D3 is produced in the skin following exposure to UVB light from the sun or artificial sources, and occurs naturally in a small range of foods.More recently, several reports underlined the impact of vitamin D on the prevalence and consequences of inadequate vitamin D intake and the research supporting its benefits for alleviating chronic musculoskeletal pain and fatigue syndromes in outpatients. Experts have recommended that vitamin D inadequacy should be addressed in all patients with bone or joint pain, myalgia, fibromyalgia, or chronic fatigue syndrome. It appears that soothing the daily musculoskeletal pain by supplementation of vitamin D may be a simple, well tolerated, and cost-effective modality. Aim of study: To study the potential therapeutic effects of vitamin D supplementation on patients with persistent musculo-skeletal pain. Clinicalparameters, visual analog score,short form McGill Pain Questionnaire,patient global perceived effect, quality of life assessed by SF-36 Questionnaire and laboratory parameters, the levels of 25 OH-Vitamin D, CRP, IL-6, IL-8, TNF and prostaglandin E will be assessed.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Meir Medical Center
Treatments:
Ergocalciferols
Vitamin D
Vitamins
Criteria
Inclusion Criteria:

- We enrolled patients suffering from chronic musculo-skeletal pain (low back pain,
fibromyalgia, chronic widespread pain) at least 6 months.

Exclusion Criteria:

- Patients with low compliance

- Allergy for vit D