The main study will be a two arm 10-month, cross-over randomized controlled trial of 200
participants treated with end-stage-kidney-disease treated with in-center hemodialysis in the
Seattle and San Francisco area comparing a strategy of targeting home vs. pre-dialysis
systolic blood pressure <140 mmHg to reduce rates of intradialytic hypotension. The target
systolic blood pressure of <140 mmHg in both treatment groups will be achieved using an
algorithm of dry weight adjustment and anti-hypertensive medication adjustment.
Phase:
N/A
Details
Lead Sponsor:
University of Washington
Collaborators:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) University of California, San Francisco