Overview

The Hemostatic and Hemodynamic Effects of Adrenaline During Endoscopic Sinus Surgery

Status:
Unknown status
Trial end date:
2010-04-01
Target enrollment:
Participant gender:
Summary
Obtaining adequate hemostasis is crucial during endoscopic sinus surgery. Submucosal injection of local anaesthetic containing adrenaline has frequently been used to improve surgical milieu. However, injection of adrenaline has potential side effects including tachycardia, hypertension as well as inducing arrhythmia. The aim of this randomized clinical trial is to assess the hemodynamic and hemostatic effects of two different concentrations of adrenaline in local anaesthetic used during endoscopic sinus surgery.
Phase:
Phase 3
Details
Lead Sponsor:
University of Toronto
Treatments:
Epinephrine
Epinephryl borate
Hemostatics
Lidocaine
Racepinephrine