The Efficiency of Postoperative Antibiotics in Orthognathic Surgery
Status:
Unknown status
Trial end date:
2017-03-01
Target enrollment:
Participant gender:
Summary
Orthognathic surgery is the state of art of the maxillofacial surgery, it fix and normalize
facial abnormalities and create a harmony between the different tissues compounding the face
(bone, soft tissue and dental structures). It is a common procedure and it is done in order
to correct a dentofacial and skeletal deformities.
There is an inevitable risk of complications with this type of surgery. While postoperative
infections are the most common complication (2% to 33.4%).
preoperative administration of antibiotics have been proven to be effective in reducing the
postoperative infection rate, while, the quality of the currently available literature in
prescribing continues postoperative antibiotics is questionable and there is still no
consensus on its efficacy.
Unwise administration of antibiotics may cause several unwanted side effects such as
gastrointestinal symptoms, allergy reactions, high costs, etc… while the most worrisome side
effect is a bacterial resentence.
The objective of this study is to investigate the efficacy of postoperative antibiotics. And
will try to state a consensus in prescribing postoperative antibiotics. By conducting a
prospective, randomized, double-blind, placebo-controlled study, that will explore and
analyze the efficacy of postoperative administration of Amoxicillin Clavulanate versus
placebo in reducing the rate of postoperative infections in 60 healthy patients.