Overview

The Efficacy of the Traditional Chinese Medicine Fangji Huangqi Pill Combined With Mobic on Active Knee Osteoarthritis

Status:
Unknown status
Trial end date:
2018-12-31
Target enrollment:
0
Participant gender:
All
Summary
Knee osteoarthritis (KOA) is known as degenerative joint disease, which is the most common form of arthritis and the leading cause of disability, loss of function and pain worldwide. Effective therapy to manage RA is still lack at present. Fangji Huangqi pill (FHP) is a Chinese medicine which has been widely used in treating KOA in China for hundreds of years to relieve pain, reduce swelling and protect the affected joints from further degeneration. However, no certain evidence to show the effect of FHP for the management of active KOA.
Phase:
Phase 2/Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Cui xuejun
Shanghai University of Traditional Chinese Medicine
Treatments:
Meloxicam
Criteria
Inclusion Criteria:

- Meet the diagnostic criteria for knee osteoarthritis (American College of Rheumatology
criteria)

- Grade 0-3 on the Kellgren-Lawrence grading system

- No serious medical history

- No known drug allergies

- No steroids, glucosamine, chondroitin sulfate, sodium hyaluronate before Fangji
Huangqi pill treatment within 1 month

Exclusion Criteria:

- Combined with other disease such as rheumatoid arthritis, lupus arthritis and et. al

- Grade 4 on the Kellgren-Lawrence grading system

- Allergy to study drug

- Participating in other clinical trial

- Unwilling to give informed consent