The Efficacy of Tranexamic Acid in the Treatment of Lichen Planus Pigmentosus and Erythema Dyschromicum Perstans
Status:
Recruiting
Trial end date:
2021-05-30
Target enrollment:
Participant gender:
Summary
There are currently no effective treatments for lichen planus pigmentosus (LPP) and erythema
dyschromicum perstans (EDP). Tranexamic acid, which may downregulate pigmentation through a
reduction in plasmin, has been shown to decrease pigmentation in patients with melasma,
another pigmentary disorder. Given that LPP, EDP, and melasma are all disorders of
pigmentation with dermal involvement, it is possible that tranexamic acid can also reduce
pigmentation in LPP and EDP as well.