The aim of this prospective double blinded randomised study is to investigate the efficacy of
symbiotic preparation which contains lactobacillus casei, L. rhamnosus, L. plantarum,
Bifidobacterium lactis, fructo and galactooligosaccharide on cytokines as interferon-gama
acting on Th1 pathway, interleukin -5 acting on Th2, interleukin -10 acting on T regulatory
pathway, and interleukin -17 acting on Th-17 pathway that were related with necrotizing
enterocolitis pathogenesis in very low birth weight neonates.
Phase:
Phase 3
Details
Lead Sponsor:
Zeynep Kamil Maternity and Pediatric Research and Training Hospital