The Efficacy of Pregabalin on the Duration of the Spinal Anesthesia and the Early Postoperative Pain After Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2021-08-25
• Target enrollment: 0
• Participant gender: All

Summary

the purpose of this study is to evaluate the effectiveness of administration of pregabalin 2 hours preoperatively on the onset and the duration of the spinal anesthesia in total knee arthroplasty and the role of pregabalin in postoperative analgesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Pregabalin

Criteria

Inclusion Criteria:

• the ages of 40 and 70 years

• height 155-170 cm

• American Society of Anesthesiologists grade I or II .

• patients underwent total knee arthroplasty under spinal anesthesia

Exclusion Criteria:

• patients known to be allergic to any medicines.

• patients had a history of drug or alcohol abuse.

• patients were taking opioids or sedative medications,

• patients Inability to communicate with investigators to evaluate the postoperative pain

• patients were in need for postoperative ICU hospitalization .

• patients had a history of psychiatric conditions.

• Patients with a history of taking pregabalin or gabapentin .